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KMID : 0942820110100020123
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Journal of Korean Brain Tumor Society
2011 Volume.10 No. 2 p.123 ~ p.126
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Hemangiopericytoma with Aggressive Extraneural Metastasis
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Seo Jin-Ho
Jung Chul-Ku
Kim Hyun-Woo
Ha Ho-Gyun
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Abstract
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The authors describe a case of the intracranial hemangioperictyoma with multiple extradural, extraneural metastases to cervical vertebra, thoracic spinal cord, lung, chest wall, and intra-abdominal organs. A 41-year-old man presented with right-sided peripheral type facial palsy, decreased visual acuity, deafness, intermittent headache. Initial neuroimaging studies suggested malignant meningioma or hemangiopericytoma with involvement of the internal auditory canal. A surgical intervention was performed and the tumor was gross-totally removed. The histopathological diagnosis was confirmed as hemangiopericytoma. After 4 years later, he had a C5 metastasis, which had been treated with C5 corpectomy with cervical fusion. Further evaluations revealed multiple metastases in liver, lung, pancreas, periaorta area, thoracic and lumbar vertebra. At liver biopsy, hemangiopericytoma was confirmed, which had a similar character to an intracranial lesion. The patient was treated with radiotherapy, chemotherapy and cyberkife-sterotactic radiosurgery (CK-SRS), but dead due to medical problem 7 years after initial diagnosis. Although the hemangiopericytomas have a strong tendency to both local recurrence and extracranial metastasis, in our case, there was no local recurrence in brain parenchyme and no severe neurologic deficits for living after aggressive treatment. We carefully suggest that aggressive treatment with combined modality for hemangiopericytoma may influence on tumor control and to maintain stable neurological state without severe deficits.
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KEYWORD
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Hemangiopericytoma, Metastasis, Recurrence
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